Yuying Tan Selected Research

Pancreatic Neoplasms (Pancreatic Cancer)

6/2023	3D Chemical Imaging by Fluorescence-detected Mid-Infrared Photothermal Fourier Light Field Microscopy.
1/2023	Profiling single cancer cell metabolism via high-content SRS imaging with chemical sparsity.
1/2021	Triple-Methyl Blockade With Recombinant Methioninase, Cycloleucine, and Azacitidine Arrests a Pancreatic Cancer Patient-Derived Orthotopic Xenograft Model.
11/2020	Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model.
2/2018	Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models.
1/2018	Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer.
1/2018	Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer.

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Yuying Tan Research Topics

Disease

57	Neoplasms (Cancer) 01/2024 - 08/2002
8	Ovarian Neoplasms (Ovarian Cancer) 01/2024 - 01/2019
7	Pancreatic Neoplasms (Pancreatic Cancer) 06/2023 - 01/2018
7	Melanoma (Melanoma, Malignant) 11/2020 - 10/2017
5	Colorectal Neoplasms (Colorectal Cancer) 03/2020 - 09/2019
4	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2018
4	Sarcoma (Soft Tissue Sarcoma) 01/2020 - 01/2018
3	Colonic Neoplasms (Colon Cancer) 04/2022 - 12/2019
3	Osteosarcoma (Osteogenic Sarcoma) 01/2020 - 01/2018
3	Anaphylaxis (Anaphylactic Shock) 01/2019 - 03/2004
3	Ewing Sarcoma (Sarcoma, Ewing) 01/2019 - 05/2017
2	Inflammation (Inflammations) 02/2021 - 01/2019
2	Triple Negative Breast Neoplasms 11/2020 - 09/2020
2	Obesity 05/2020 - 03/2020
2	Synovial Sarcoma (Synovioma) 10/2018 - 04/2018
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2023
1	Opportunistic Infections (Opportunistic Infection) 01/2023
1	Autoimmune Diseases (Autoimmune Disease) 01/2023
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2022
1	Fibrosis (Cirrhosis) 01/2022
1	Hypoxia (Hypoxemia) 02/2021
1	Wounds and Injuries (Trauma) 02/2021
1	Suppuration 02/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2021
1	Liposarcoma 05/2020
1	Prostatic Neoplasms (Prostate Cancer) 05/2020
1	Non-alcoholic Fatty Liver Disease 05/2020
1	Lymphatic Metastasis 03/2020
1	Necrosis 09/2019
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2019
1	Infections 01/2019
1	Fibrosarcoma 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2019

Drug/Important Bio-Agent (IBA)

43	L-methionine gamma-lyaseIBA 01/2021 - 08/2002
31	Methionine (L-Methionine)FDA Link 01/2021 - 12/2003
10	Proteins (Proteins, Gene)FDA Link 06/2023 - 01/2019
9	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2020 - 09/2014
6	Fluorouracil (Carac)FDA LinkGeneric 03/2020 - 09/2014
6	LyasesIBA 01/2019 - 07/2004
5	EnzymesIBA 10/2022 - 12/2003
4	Temozolomide (Temodar)FDA LinkGeneric 03/2020 - 10/2017
3	LipidsIBA 01/2024 - 03/2020
3	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 08/2002
3	Gemcitabine FDA Link 01/2021 - 01/2018
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2022 - 01/2022
2	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 09/2014
2	PlatinumIBA 01/2022 - 01/2021
2	Azacitidine (5 Azacytidine)FDA Link 01/2021 - 01/2020
2	pazopanib FDA Link 03/2020 - 03/2020
2	Leucovorin (Folinic Acid)FDA Link 03/2020 - 12/2019
2	TrabectedinIBA 12/2019 - 11/2019
2	Caffeine (No Doz)FDA LinkGeneric 09/2019 - 10/2018
2	Cytotoxins (Cytolysins)IBA 01/2019 - 01/2016
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2019 - 03/2004
2	Indicators and Reagents (Reagents)IBA 01/2016 - 09/2014
2	Amino Acids FDA Link 09/2008 - 12/2003
1	RNA (Ribonucleic Acid)IBA 01/2024
1	AcidsIBA 01/2023
1	UbiquitinIBA 01/2023
1	Cullin Proteins (Cullins)IBA 01/2023
1	Ligases (Synthetase)IBA 01/2023
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2022
1	ChemokinesIBA 06/2022
1	Competitive Endogenous RNAIBA 04/2022
1	Long Noncoding RNAIBA 04/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	OsteopontinIBA 01/2022
1	NeuropeptidesIBA 02/2021
1	Oxygen (Dioxygen)IBA 02/2021
1	Substance PIBA 02/2021
1	Carboplatin (JM8)FDA LinkGeneric 01/2021
1	Glutathione (Reduced Glutathione)IBA 01/2021
1	RetinoidsIBA 01/2021
1	CycloleucineIBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	5-Methylcytosine (5 Methylcytosine)IBA 01/2021
1	tigatuzumabIBA 11/2020
1	AntigensIBA 11/2020
1	LigandsIBA 11/2020
1	Insulin (Novolin)FDA Link 05/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 03/2020
1	Decitabine FDA Link 01/2020
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2020
1	Irinotecan (Camptosar)FDA LinkGeneric 12/2019
1	MicroRNAs (MicroRNA)IBA 01/2019
1	Cytochromes c (Cytochrome c)IBA 01/2019
1	methaneselenolIBA 01/2019
1	Selenomethionine (Sethotope)FDA Link 01/2019
1	StaurosporineIBA 01/2019

Therapy/Procedure

19	Therapeutics 01/2021 - 01/2005
14	Drug Therapy (Chemotherapy) 01/2024 - 08/2004
5	Aftercare (After-Treatment) 01/2021 - 01/2018
2	Injections 05/2020 - 01/2018
1	Immunotherapy 04/2022
1	Neoadjuvant Therapy 01/2021
1	Chemoradiotherapy 01/2021
1	Laparotomy 11/2020
1	Hair Removal (Depilation) 01/2019
1	Laminectomy 01/2019
1	Intraperitoneal Injections 01/2019